Briarwood, NY, United States of America

Nilesh Zaware


 

Average Co-Inventor Count = 3.0

ph-index = 1


Location History:

  • New York, NY (US) (2018 - 2019)
  • Briarwood, NY (US) (2019 - 2020)

Company Filing History:


Years Active: 2018-2025

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6 patents (USPTO):Explore Patents

Title: Nilesh Zaware: Innovator in Anti-Cancer Research

Introduction

Nilesh Zaware is a prominent inventor based in Briarwood, NY (US). He has made significant contributions to the field of medicinal chemistry, particularly in the development of compounds with potential anti-cancer properties. With a total of 6 patents to his name, Zaware's work is paving the way for innovative treatments in oncology.

Latest Patents

Zaware's latest patents include groundbreaking research on bicyclic inhibitors of CBX chromodomains. This patent discloses a genus of bicyclic inhibitors that target CBX proteins, which are crucial in various biological processes. The compounds are designed to be indoles or benzimidazoles, showcasing a particular subgenus of 1,3-disubstituted-1,3-dihydro-2H-benzo[d]imidazol-2-imines.

Another notable patent focuses on heterocyclic constrained tricyclic sulfonamides as anti-cancer agents. This research reveals a genus of arylsulfonamide derivatives that induce FOXO1 transcription factor translocation to the nucleus. By modulating PP2A, these compounds exhibit anti-proliferative effects and are useful in treating various disorders, including cancer. They can also be combined with other drugs to restore sensitivity to chemotherapy in resistant cases.

Career Highlights

Nilesh Zaware is currently affiliated with the Icahn School of Medicine at Mount Sinai, where he continues to advance his research in medicinal chemistry. His work is characterized by a strong focus on developing innovative therapeutic agents that can significantly impact cancer treatment.

Collaborations

Zaware collaborates with esteemed colleagues, including Michael H Ohlmeyer and Ming-Ming Zhou. These partnerships enhance the research efforts and contribute to the development of effective anti-cancer therapies.

Conclusion

Nilesh Zaware's innovative work in the field of medicinal chemistry, particularly in anti-cancer research, highlights his commitment to improving treatment options for patients. His patents reflect a deep understanding of complex biological mechanisms and a dedication to advancing medical science.

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