The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2018
Filed:
Aug. 29, 2014
Applicant:
Icahn School of Medicine AT Mount Sinai, New York, NY (US);
Inventors:
Ming-Ming Zhou, Old Greenwich, CT (US);
Michael Ohlmeyer, Plainsboro, NJ (US);
Adam Vincek, Tarrytown, NY (US);
Nilesh Zaware, New York, NY (US);
Assignee:
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/136 (2006.01); A61K 31/166 (2006.01); A61K 31/18 (2006.01); A61K 31/195 (2006.01); A61K 31/196 (2006.01); A61K 31/245 (2006.01); A61K 31/277 (2006.01); A61K 31/404 (2006.01); A61K 31/4184 (2006.01); A61K 31/4192 (2006.01); A61K 31/44 (2006.01); A61K 31/4402 (2006.01); A61K 31/4406 (2006.01); A61K 31/4409 (2006.01); A61K 31/4468 (2006.01); A61K 31/47 (2006.01); A61K 31/4965 (2006.01); A61K 31/498 (2006.01); A61K 31/517 (2006.01); A61K 31/5375 (2006.01); A61K 45/06 (2006.01); C07D 209/08 (2006.01); C07D 209/40 (2006.01); C07D 211/58 (2006.01); C07D 213/74 (2006.01); C07D 213/75 (2006.01); C07D 213/76 (2006.01); C07D 215/06 (2006.01); C07D 215/38 (2006.01); C07D 217/02 (2006.01); C07D 239/74 (2006.01); C07D 241/20 (2006.01); C07D 241/42 (2006.01); C07D 249/04 (2006.01); C07D 249/06 (2006.01); C07D 295/16 (2006.01); C07D 295/21 (2006.01); C07C 225/20 (2006.01); C07C 229/48 (2006.01); C07C 229/56 (2006.01); C07C 229/60 (2006.01); C07C 229/68 (2006.01); C07C 237/30 (2006.01); C07C 237/40 (2006.01); C07C 255/58 (2006.01); C07C 311/38 (2006.01); C07D 235/26 (2006.01);
U.S. Cl.
CPC ...
C07C 225/20 (2013.01); A61K 31/136 (2013.01); A61K 31/166 (2013.01); A61K 31/18 (2013.01); A61K 31/195 (2013.01); A61K 31/196 (2013.01); A61K 31/245 (2013.01); A61K 31/277 (2013.01); A61K 31/404 (2013.01); A61K 31/4184 (2013.01); A61K 31/4192 (2013.01); A61K 31/44 (2013.01); A61K 31/4402 (2013.01); A61K 31/4406 (2013.01); A61K 31/4409 (2013.01); A61K 31/4468 (2013.01); A61K 31/47 (2013.01); A61K 31/498 (2013.01); A61K 31/4965 (2013.01); A61K 31/517 (2013.01); A61K 31/5375 (2013.01); A61K 45/06 (2013.01); C07C 229/48 (2013.01); C07C 229/56 (2013.01); C07C 229/60 (2013.01); C07C 229/68 (2013.01); C07C 237/30 (2013.01); C07C 237/40 (2013.01); C07C 255/58 (2013.01); C07C 311/38 (2013.01); C07D 209/08 (2013.01); C07D 209/40 (2013.01); C07D 211/58 (2013.01); C07D 213/74 (2013.01); C07D 213/75 (2013.01); C07D 213/76 (2013.01); C07D 215/06 (2013.01); C07D 215/38 (2013.01); C07D 217/02 (2013.01); C07D 235/26 (2013.01); C07D 239/74 (2013.01); C07D 241/20 (2013.01); C07D 241/42 (2013.01); C07D 249/04 (2013.01); C07D 249/06 (2013.01); C07D 295/16 (2013.01); C07D 295/21 (2013.01);
Abstract
Cyclic vinylogous amides of Formula I are disclosed The compounds are useful for treating diseases that arise from inappropriate activity of proteins containing an acetyl-lysine. The compositions comprise a genus of cyclic vinylogous amides that are inhibitors of bromodomain.