Location History:
- Ballwin, MO (US) (2004)
- Grafton, WI (US) (2005 - 2006)
- St. Charles, IL (US) (2012 - 2013)
Company Filing History:
Years Active: 2004-2013
Title: **Innovations by Nathan W. Stehle: Pioneering Protease Inhibitors**
Introduction
Nathan W. Stehle, a notable inventor based in Grafton, Wisconsin, has made significant contributions to the field of biochemistry through his innovative work in protease inhibitors. With a total of five patents to his name, his inventions are geared towards addressing critical health issues linked to protease activity.
Latest Patents
Among his latest patents, Stehle has developed compounds such as piperidinyl- and piperazinyl-sulfonylmethyl hydroxamic acids, notable for their ability to inhibit matrix metalloproteinase (MMP) and aggrecanase activities. These hydroxamic acids, which can be utilized in various compositions and treatments, provide potential therapeutic benefits for conditions related to MMP activity.
Another significant invention is the aromatic sulfone hydroxamic acid metalloprotease inhibitor. This treatment process focuses on an effective administration of specific aromatic sulfone hydroxamic acids, showcasing selective inhibition of harmful matrix metalloproteinase enzymes. The patented formulations hold promise for advancing medical treatments by targeting pathological processes associated with MMP activity.
Career Highlights
Stehle's career has been firmly rooted in innovation, primarily through his role at Pharmacia Corporation. His extensive research has culminated in various patents that reflect his dedication to developing solutions for complex biological challenges. His work is instrumental in enhancing our understanding of protease functions and their impact on health.
Collaborations
During his career, Stehle has collaborated with esteemed colleagues such as Thomas E. Barta and Daniel Paul Becker. These partnerships have undoubtedly enriched his research endeavors, fostering an environment of shared knowledge and innovation in developing effective protease inhibitors.
Conclusion
Nathan W. Stehle's contributions to the field of protease inhibition illustrate the vital role of innovation in addressing complex health issues. His patented inventions not only pave the way for advancements in therapeutic strategies but also embody the spirit of scientific exploration that drives modern biochemistry forward.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.