Natasha Barascuk Michaelsen

Title: Innovations by Natasha Barascuk Michaelsen

Introduction

Natasha Barascuk Michaelsen is a prominent inventor based in Gentofte, Denmark. She has made significant contributions to the field of biomedical research, particularly in the area of cardiovascular disease risk assessment. With a total of five patents to her name, her work has the potential to impact clinical practices and improve patient outcomes.

Latest Patents

One of her latest patents involves biochemical markers for cardiovascular disease (CVD) risk assessment. This patent provides a method of bioassay for the quantification of N- or C-terminal neo-epitope biomarkers formed by the cleavage of proteins such as CRP, ApoE, lumican, versican, perlecan, decorin, biglycan, or elastin by a proteinase. The method includes contacting a biofluid sample with an antibody reactive with the neo-epitope biomarker and determining the level of binding of the antibody to the biomarker in the sample. This assay is predictive of the risk of cardiovascular disease events. Another patent focuses on a method of bioassay for the quantification of peptide fragments comprising a neo-epitope formed by the cleavage of mimecan, a protein found in atherosclerotic plaques, by a proteinase. In this method, a sample, such as urine or serum, is contacted with an antibody reactive with the neo-epitope, and the level of binding of the antibody to peptide fragments in the sample is determined. This assay is also predictive of the risk of cardiovascular disease events.

Career Highlights

Natasha has worked with notable companies in the biomedical field, including Nordic Bioscience A/S. Her experience in these organizations has allowed her to develop and refine her innovative approaches to disease risk assessment.

Collaborations

Some of her notable coworkers include Morten A Karsdal and Sanne S Veidal, who have collaborated with her on various projects related to her research.

Conclusion

Natasha Barascuk Michaelsen's contributions to the field of cardiovascular disease risk assessment through her innovative patents highlight her role as a leading inventor in biomedical research. Her work continues to pave the way for advancements in clinical diagnostics and patient care.