The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2017
Filed:
Dec. 07, 2015
Sanne S. Veidal, Olstykke, DK;
Morten A. Karsdal, Kobenhavn O, DK;
Diana J. Oersnes-leeming, Klampenborg, DK;
Natasha Barascuk Michaelsen, Gentofte, DK;
Helene Skjot-arkil, Kolding, DK;
Antonio Segovia-silvestre, Copenhagen, DK;
Efstathios Vassiliadis, Hammel, DK;
Sanne S. Veidal, Olstykke, DK;
Morten A. Karsdal, Kobenhavn O, DK;
Diana J. Oersnes-Leeming, Klampenborg, DK;
Natasha Barascuk Michaelsen, Gentofte, DK;
Helene Skjot-Arkil, Kolding, DK;
Antonio Segovia-Silvestre, Copenhagen, DK;
Efstathios Vassiliadis, Hammel, DK;
Nordic Bioscience A/S, Herlev, DK;
Abstract
Provided herein are methods of diagnosis or of quantitation of fibrosis. An immunoassay is conducted to measure neo-epitope containing protein fragments of collagen type III, collagen type I, collagen type IV, collagen type V, or collagen type VI, elastin, biglycan, decorin, lumican, versican, perlecan, neurocan, brevican, fibromodulin, serglycin, syndecan, betaglycan, vimentin, or C-reactive protein naturally present in a biofluid sample obtained from a patient. An above normal elevation of the measured protein fragments in the patient is associated with the presence or extent of fibrosis.