The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2018
Filed:
May. 04, 2012
Natasha Barascuk Michaelsen, Kobenhavn S, DK;
Federica Genovese, Kobenhavn O, DK;
Morten Karsdal, Kobenhavn O, DK;
Diana Julie Leeming, Espergaerde, DK;
Natasha Barascuk Michaelsen, Kobenhavn S, DK;
Federica Genovese, Kobenhavn O, DK;
Morten Karsdal, Kobenhavn O, DK;
Diana Julie Leeming, Espergaerde, DK;
Nordic Biociences A/S, Herlev, DK;
Abstract
A method of bioassay for the quantification of peptide fragments comprising a neo-epitope formed by cleavage of mimecan, a protein of an atherosclerotic plaque, by a proteinase is provided. In the method a sample, such as urine or serum, is contacted with an antibody reactive with the neo-epitope and the level of binding of the antibody to peptide fragments in the sample is determined. The assay is predictive of risk of cardiovascular disease events.