Location History:
- Jamaica Plain, MA (US) (2014 - 2021)
- Lexington, MA (US) (2017 - 2023)
Company Filing History:
9 out of 86 
2 out of 1,179 
1 out of 25 
Years Active: 2014-2025
Title: Innovations of Muthuraman Meiyappan in Biochemical Patents
Introduction
Muthuraman Meiyappan is a prominent inventor based in Jamaica Plain, MA. He has made significant contributions to the field of biochemical research, holding a total of 11 patents. His work primarily focuses on enzyme purification techniques and therapeutic advancements, showcasing his innovative spirit and dedication to science.
Latest Patents
Among his latest patents, Meiyappan has developed an affinity purification method for glycosidase-cleaving enzymes. This invention relates to an affinity resin that is functionalized with small molecule inhibitors of various glycoside-cleaving enzymes. This method is pivotal for purifying these enzymes produced in a cell line, enhancing efficiency in biochemical applications.
Another noteworthy patent pertains to a therapeutic fusion protein that includes an alpha-N-acetylglucosaminidase and a lysosomal targeting moiety. This invention presents methods for treating Sanfilippo syndrome type B, particularly through intrathecal administration of a Naglu protein. The innovation shows promise for developing effective treatments for this rare genetic disorder.
Career Highlights
Throughout his career, Meiyappan has worked with prominent companies such as Shire Human Genetic Therapies and Synageva Biopharma Corporation. His experience within these leading organizations has allowed him to contribute significantly to the biopharmaceutical industry and the development of innovative therapies.
Collaborations
Meiyappan has collaborated with notable colleagues, including Michael F. Concino and Angela Norton. These partnerships reflect his commitment to advancing research and fostering teamwork within the scientific community.
Conclusion
Muthuraman Meiyappan's contributions to the field of biochemistry through his patents highlight his innovative approach to solving complex medical challenges. His work not only advances scientific knowledge but also holds the potential to improve patient outcomes in genetic diseases. As he continues to innovate, his impact on the field will undoubtedly inspire future generations of inventors and researchers.