The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2020
Filed:
Aug. 11, 2015
Shire Human Genetic Therapies, Inc., Lexington, MA (US);
Michael F. Concino, Lexington, MA (US);
Bettina Strack-Logue, Lexington, MA (US);
Muthuraman Meiyappan, Lexington, MA (US);
Angela W. Norton, Lexington, MA (US);
Bohong Zhang, Lexington, MA (US);
Andrea Iskenderian, Lexington, MA (US);
Lieh Yoon Low, Lexington, MA (US);
Dianna Lundberg, Lexington, MA (US);
Alla Romashko, Lexington, MA (US);
Hicham Naimy, Lexington, MA (US);
Shire Human Genetic Therapies, Inc., Lexington, MA (US);
Abstract
A targeted therapeutic including a lysosomal enzyme and a lysosomal targeting moiety that is a peptide containing at least one N-linked glycosylation site. Methods of producing the targeted therapeutic may include nucleotide acids encoding the same and host cells co-expressing GNPT. Pharmaceutical compositions comprising the targeted therapeutic and methods of using the same to treat a lysosomal storage disease.