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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11685912 B1

PDFFull Text
Date of Patent:
Jun. 27, 2023

Filed:

Mar. 05, 2019

Affinity purification of glycosidase-cleaving enzymes

Applicant:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Inventors:

Brian Dwyer, Lexington, MA (US);

Bohong Zhang, Lexington, MA (US);

Jun Hu, Lexington, MA (US);

Muthuraman Meiyappan, Lexington, MA (US);

Thomas Miller, Lexington, MA (US);

Paul McLean, Lexington, MA (US);

Clark Pan, Lexington, MA (US);

Assignee:

TAKEDA PHARMACEUTICAL COMPANY LIMITED, Osaka, JP;

Attorney:

Troutman Pepper Hamilton Sanders LLP

Primary Examiner:

Vishal V Vasisth

Int. Cl.
CPC ...
C12N 9/40 (2006.01); B01J 20/286 (2006.01); B01J 20/289 (2006.01); B01J 20/32 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2465 (2013.01); B01J 20/286 (2013.01); B01J 20/289 (2013.01); B01J 20/3219 (2013.01); B01J 20/3253 (2013.01); B01J 20/3255 (2013.01); C12Y 302/01022 (2013.01);
Abstract

The invention relates to an affinity resin functionalized with small molecule inhibitors of glycoside-cleaving enzymes, e.g., α-galactosidase A (α-Gal A), glucocerebrosidase (GCB), β-galactosidase, and acid alpha-glucosidase (GAA), and a method for purifying glycoside-cleaving enzymes produced in a cell line using the small molecule inhibitor-functionalized affinity resin.

Find Patent Forward Citations

Dwyer, Brian. (2023). Affinity purification of glycosidase-cleaving enzymes (U.S. Patent No. 11685912). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11685912

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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