Michael Steward

Title: Michael Steward: Innovator in Protein and Antigen Binding Technologies

Introduction

Michael Steward is a notable inventor based in Stevenage, GB. He has made significant contributions to the field of biotechnology, particularly in the development of modified proteins and peptides. With a total of 3 patents to his name, Steward's work has implications for various medical applications.

Latest Patents

One of Steward's latest patents focuses on modified proteins and peptides. This invention relates to modified molecules that have a reduced ability to bind to pre-existing antibodies. These modified protein and peptide molecules can include C-terminal additions, extensions, or tags, as well as specific amino acid substitutions. The patent also discusses the uses and formulations of compositions that comprise these modified molecules, which can include proteins, peptides, and antibody fragments.

Another significant patent by Steward is directed towards antigen binding constructs. This invention comprises one or two epitope binding domains separated by a single chain Fc region of an antibody. Each epitope binding domain is capable of binding to VEGF. The patent also covers pharmaceutical compositions that include these constructs and their applications in treating diseases associated with VEGF signaling, such as diabetic macular edema and wet age-related macular degeneration.

Career Highlights

Throughout his career, Michael Steward has worked with prominent companies in the biotechnology sector. Notably, he has been associated with Glaxo Group Limited and Domantis Limited. His work in these organizations has allowed him to contribute to groundbreaking research and development in the field.

Collaborations

Steward has collaborated with several professionals in his field, including Claire Ashman and Alan Peter Lewis. These collaborations have further enriched his research and innovation efforts.

Conclusion

Michael Steward is a distinguished inventor whose work in modified proteins and antigen binding technologies has the potential to impact medical treatments significantly. His contributions to biotechnology continue to pave the way for advancements in the field.