Company Filing History:
Years Active: 2011-2022
Title: Michael Paul Rout: Innovator in Nanobody Technology
Introduction
Michael Paul Rout is a distinguished inventor based in New York, NY, known for his significant contributions to the field of nanobody technology. With a total of four patents to his name, Rout has made remarkable advancements in the production and analysis of complex protein mixtures.
Latest Patents
Rout's latest patents include "Compositions and methods for rapid production of versatile nanobody repertoires." This invention provides compositions and methods for producing large repertoires of recombinant nanobodies with high affinities and specificities against any antigen. The patent includes methods for making and identifying nanobodies produced by camelids, as well as modifications of the nanobodies, expression vectors encoding the nanobodies, cDNAs encoding the nanobodies, and cells comprising the expression vectors and/or cDNA. Additionally, it outlines methods of making the nanobodies recombinantly, with antigen-specific nanobodies having a Kd for the antigen in a sub-micromolar range.
Another notable patent is "Apparatus and method for parallel collection and analysis of the proteome and complex compositions." This invention relates to a kit and method for the collection and analysis of complex protein mixtures. It comprises a single barrel filtration well or a multi-well filtration plate designed for accurate, automated, high-throughput protein analysis by affinity chromatography.
Career Highlights
Throughout his career, Michael Paul Rout has worked with prestigious organizations such as The Rockefeller University and Orochem Technologies, Inc. His work has significantly impacted the field of protein analysis and nanobody technology.
Collaborations
Rout has collaborated with notable colleagues, including Brian T Chait and Alan J Tackett, further enhancing the scope and impact of his research.
Conclusion
Michael Paul Rout's innovative work in nanobody technology and protein analysis has established him as a leading figure in his field. His patents reflect a commitment to advancing scientific knowledge and practical applications in biotechnology.
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