Santa Clara, CA, United States of America

Michael D Ruehle

This inventor holds 68 USPTO granted patents and 22 published patent applications and 11 EPO patents, primarily in Bioinformatics Systems (CPC class H01L). Top assignees: Edico Genome Corporation, Intel Corporation, Illumina Corporation. Active years: 2003-2026.

USPTO Granted Patents = 68 

% Patents Active = 57.4

 

Average Co-Inventor Count = 1.7

ph-index = 12

Forward Citations = 608(Granted Patents)

Forward Citations (Not Self Cited) = 441(Dec 10, 2025)


Inventors with similar research interests:


Location History:

  • Santa Clara, CA (US) (2003 - 2007)
  • La Joya, CA (US) (2016)
  • Forth Worth, TX (US) (2017)
  • Albuquerque, NM (US) (2009 - 2018)
  • San Diego, CA (US) (2007 - 2019)
  • Dallas, TX (US) (2018 - 2020)
  • La Jolla, CA (US) (2016 - 2021)
  • Fort Worth, TX (US) (2018 - 2023)

Company Filing History:


Years Active: 2003-2026

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Areas of Expertise:
K-mer Graph Generation
Gene Fusion Detection
De Bruijn Graph
Genomic Mapping
DNA Processing
RNA Processing
NFA Matching
DFA Compression
Integrated Circuit
Next Generation Sequencing
Bioinformatics Infrastructure
Dynamic Genome Reference
68 patents (USPTO):Explore Patents

Title: Innovations of Michael D Ruehle: Pioneering Advances in Bioinformatics

Introduction

Michael D Ruehle, a prominent inventor based in Santa Clara, CA, holds an impressive portfolio of 61 patents. His groundbreaking work focuses primarily on bioinformatics systems and methods, harnessing the power of integrated circuit processing platforms for genetic sequence analysis.

Latest Patents

Among his latest innovations are two notable patents that showcase his expertise. The first, titled "Bioinformatics systems, apparatuses, and methods executed on an integrated circuit processing platform," describes a system and method for executing bioinformatics analysis on genetic sequence data. This invention employs an integrated circuit consisting of hardwired digital logic circuits interconnected by physical electrical links, featuring an input connected to electronic data sources for genomic data processing.

The second patent, "Flexible seed extension for hash table genomic mapping," outlines methods and apparatuses aimed at enhancing the mapping of reads through an innovation in hash table configuration. This invention details obtaining a seed of nucleotides from a reference sequence, creating a seed extension tree, and effectively storing interval information to facilitate genomic mapping.

Career Highlights

Michael has made significant contributions to technology through his work with notable companies such as Edico Genome Corporation and Intel Corporation. His career is marked by a commitment to advancing bioinformatics, demonstrating his inventive spirit and dedication to solving complex problems in the field.

Collaborations

Throughout his career, Michael has collaborated with esteemed colleagues, including Robert J McMillen and Pieter van Rooyen. These partnerships have fostered an environment of innovation, allowing for the successful development of transformative technologies in bioinformatics.

Conclusion

Michael D Ruehle's contributions to the field of bioinformatics are noteworthy, characterized by his numerous patents and significant collaborations. His innovative systems and methods continue to influence the landscape of genetic research and data analysis, marking him as a key figure in contemporary technological advancements.

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