Mie, Japan

Masayasu Kurono


Average Co-Inventor Count = 6.5

ph-index = 11

Forward Citations = 640(Granted Patents)

Forward Citations (Not Self Cited) = 622(Dec 10, 2025)


Inventors with similar research interests:


Location History:

  • Sasao, JP (1989)
  • Mie, JP (1987 - 1995)
  • Aichi, JP (1989 - 1995)
  • Nagoya, JP (1985 - 1996)
  • Mieken, JP (1990 - 1996)

Company Filing History:


Years Active: 1985-1996

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Areas of Expertise:
Liposome Technology
Motilin Preparations
Hydantoin Derivatives
Nootropic Agents
Vasoactive Intestinal Polypeptide
Pharmaceutical Compositions
DNA Cloning Techniques
Diabetes Treatment
Immunity Adjusting Compounds
Gastrointestinal Ulcer Treatment
Optically Active Compounds
Protein Supplementation
71 patents (USPTO):Explore Patents

Title: **Masayasu Kurono: Innovations in Gene Delivery and Alzheimer's Treatment**

Introduction

Masayasu Kurono, based in Mie, Japan, is a distinguished inventor known for his significant contributions to the fields of gene delivery and pharmaceuticals. With an impressive portfolio of 71 patents, he has played a crucial role in advancing innovative solutions for medical challenges, particularly in treating neurodegenerative diseases.

Latest Patents

Among his latest patents, Kurono has developed a novel liposome for entrapping genes aimed at enhancing gene entrapping efficiency. This innovation focuses on the formation of positively charged liposome membranes, utilizing constitutional lipids such as N-(α-trimethylammonioacetyl)-didodecyl-D-glutamate chloride (TMAG), dilauroylphosphatidylcholine (DLPC), and dioleoylphosphatidylethanolamine (DOPE) in a specific molar ratio of 1:2:2. Through a specialized vortex treatment, these liposomes are prepared with multi-layers to effectively entrap genes. Additionally, he has developed a compound designed to bind muscarinic receptors in the brain, offering potential as an effective ingredient for preventing and treating senile dementias, particularly Alzheimer's disease.

Career Highlights

Throughout his career, Masayasu Kurono has worked with several notable institutions, including Sanwa Kagaku Kenkyusho Co., Ltd. and Kabushiki Kaisha Vitamin Kenkyuso. His innovative work has not only resulted in new therapeutic techniques but has also laid the groundwork for ongoing research in gene therapy and Alzheimer’s treatments.

Collaborations

Kurono has collaborated with esteemed coworkers, such as Kiichi Sawai and Takahiko Mitani. These partnerships have fostered a productive exchange of ideas and innovations that have significantly enhanced his research and development efforts.

Conclusion

Masayasu Kurono's work exemplifies the power of innovation in the medical field. His contributions to gene delivery methods and Alzheimer’s disease treatment highlight the importance of creative thinking and collaboration in advancing healthcare solutions. As he continues to produce influential patents, the potential benefits of his inventions will undoubtedly pave the way for future breakthroughs in medicine.

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