Location History:
- Nagoya, JP (1982)
- Yokohama, JP (1988)
- Mobara, JP (1989 - 1997)
- Chiba-ken, JP (1998)
- Chiba, JP (1996 - 2002)
Company Filing History:
5 out of 1,037 
4 out of 1,788 
4 out of 1,379 
Years Active: 1982-2002
Title: Masaru Honjo: Innovator in Human Growth Hormone Production
Introduction
Masaru Honjo is a prominent inventor based in Chiba, Japan. He has made significant contributions to the field of biotechnology, particularly in the production of human growth hormones. With a total of 14 patents to his name, Honjo's work has paved the way for advancements in therapeutic applications of growth hormones.
Latest Patents
One of Honjo's latest patents is a method for the secretory production of human growth hormone. This innovative approach involves connecting a DNA encoding 20K hGH directly to a gene encoding the OppA protein secretion signal, along with a DNA encoding signal peptidase 1. The resulting recombinant plasmid is transformed into cells, allowing for the efficient secretory production of 20K hGH in the periplasm. This method not only enhances the production efficiency but also simplifies the isolation and purification of 20K hGH due to the low level of impure proteins present in the periplasm fraction. Another significant patent focuses on the therapeutic use of 20-kilodalton human growth hormone. The administration of this authentic human growth hormone can improve body composition, stimulate lipolysis, increase serum insulin-like growth factor I, and serve as a replacement therapy for patients deficient in human growth hormone.
Career Highlights
Throughout his career, Masaru Honjo has worked with notable organizations such as the Agency of Industrial Science and Technology and Mitsui Chemicals, Inc. His experience in these institutions has contributed to his expertise in biotechnology and patent development.
Collaborations
Honjo has collaborated with esteemed colleagues, including Yoshio Furutani and Hiroshi Uchida. These partnerships have further enriched his research and innovation in the field.
Conclusion
Masaru Honjo's contributions to the field of human growth hormone production exemplify the impact of innovative thinking in biotechnology. His patents and collaborations highlight the importance of research and development in advancing medical therapies.