The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 05, 1996

Filed:

Sep. 09, 1993
Applicant:
Inventors:

Masaru Honjo, Chiba, JP;

Setsuo Yoshino, Fukuoka, JP;

Akira Nakayama, Chiba, JP;

Naokazu Naito, Chiba, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ; A61K / ; C07K / ;
U.S. Cl.
CPC ...
435 694 ; 435 698 ; 435 712 ; 4353201 ; 530399 ;
Abstract

A human growth hormone having a molecular weight of 20,000 daltons can be effectively secreted and produced in the periplasm of Escherichia coli by constructing a human growth hormone secretion plasmid comprising a vector DNA replicable in E. coli and a DNA fragment including a promoter, a ribosome binding site, a secretion signal coding region, which are all those of the neutral protease gene of B. amyloliquefaciens and a gene encoding 20 kD hGH placed just downstream from the secretion signal coding region; introducing the said plasmid into E. coli; and culturing the resultant transformed cells.


Find Patent Forward Citations

Honjo, Masaru. (1996). Process for producing 20 kd human growth hormone (U.S. Patent No. 5496713). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5496713

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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