Glenview, IL, United States of America

Mary P Lambert

USPTO Granted Patents = 8 



Average Co-Inventor Count = 11.3

ph-index = 3

Forward Citations = 135(Granted Patents)


Company Filing History:


Years Active: 2001-2014

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8 patents (USPTO):Explore Patents

Title: Mary P Lambert: Innovator in Alzheimer's Disease Research

Introduction

Mary P Lambert is a prominent inventor based in Glenview, IL (US). She has made significant contributions to the field of Alzheimer's disease research, holding a total of 8 patents. Her work focuses on the development of antibodies that can differentiate between various conformations of amyloid-beta-derived diffusible ligands, which are crucial in understanding and diagnosing Alzheimer's disease.

Latest Patents

Among her latest patents is the invention of Anti-ADDL antibodies and their uses. This invention relates to antibodies that can differentially recognize multi-dimensional conformations of ADDLs. These antibodies are instrumental in distinguishing between Alzheimer's disease and control human brain extracts. They are also useful in methods for detecting ADDLs and diagnosing Alzheimer's disease. Furthermore, these antibodies block the binding of ADDLs to neurons, assembly of ADDLs, and tau phosphorylation, making them valuable in preventing and treating diseases associated with soluble oligomers of amyloid beta 1-42. Another significant patent involves monoclonal antibodies that target pathological assemblies of amyloid beta (Abeta). These antibodies bind with high specificity to soluble oligomers of Abeta and can identify endogenous Abeta oligomers in Alzheimer's disease brain slices.

Career Highlights

Mary P Lambert has worked with notable institutions, including Northwestern University and Merck Sharp & Dohme Corporation. Her research has significantly advanced the understanding of Alzheimer's disease and the development of potential therapeutic strategies.

Collaborations

Mary has collaborated with esteemed colleagues such as William L Klein and Lei Chang, contributing to the advancement of research in her field.

Conclusion

Mary P Lambert's innovative work in the development of antibodies for Alzheimer's disease has the potential to transform diagnostic and therapeutic approaches. Her contributions are vital in the ongoing battle against this debilitating condition.

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