Location History:
- Munchen, DE (2009)
- Munich, DE (2013)
- Unterschleiβheim, DE (2017)
- Unterschleissheim, DE (2016 - 2022)
Company Filing History:
2 out of 8 
1 out of 4 
1 out of 22 
Years Active: 2009-2022
Title: Innovations of Mark Harfensteller in Radiopharmaceutical Manufacturing
Introduction
Mark Harfensteller, an accomplished inventor based in Unterschleissheim, Germany, has made significant contributions to the field of radiopharmaceuticals. With a total of six patents to his name, his innovative work primarily focuses on the production of highly purified germanium (Ge) materials for medical applications.
Latest Patents
Harfensteller's latest inventions include a groundbreaking method for the manufacture of highly purified 68Ge material aimed at radiopharmaceutical purposes. This method involves creating a germanium active pharmaceutical ingredient (API) solution that adheres to the stringent Guidelines for Good Manufacturing Practices (GMP). The process utilizes a Ge stock solution as a raw material, which undergoes purification from various impurities. The innovative radiochemical method relies on a dual separation of Ge from both organic and metallic contaminants using distinct adsorbent materials. First, germanium is purified via adsorption in germanium tetrachloride form, followed by cation exchange to eliminate remaining metallic impurities. Ultimately, the Ge-API product meets regulatory specifications required for GMP production of Ge/Ga generators.
Another significant patent entails the development of a Ge/Ga generator for the continuous production of gallium (Ga) daughter nuclides. This invention meticulously adsorbs the germanium parent nuclide onto an inorganic support material, which can include oxides of metals like Vanadium, Niobium, and Tantalum. This innovative support material allows for the loading of Ge/Ga generators with up to 8000 MBq of germanium, enhancing the efficiency of pharmaceutical applications.
Career Highlights
Throughout his career, Harfensteller has been associated with prominent companies such as ITM Isotopen Technologien München AG. His expertise and innovative approach in the field of isotopes and radiopharmaceuticals have firmly established him as a leading figure in his industry.
Collaborations
Collaboration has played a vital role in Harfensteller's success. He has worked alongside talented professionals such as Tuomo Nikula and Konstantin Zhernosekov, contributing to the advancement of research and product development in radiopharmaceutical technology.
Conclusion
Mark Harfensteller's innovative contributions to the manufacturing of radiopharmaceuticals position him as a noteworthy inventor in the field. His latest patents not only promise advancements in medical applications but also exemplify his commitment to upholding the highest regulatory standards in pharmaceutical production. As he continues to innovate, the impact of his work on the healthcare industry is likely to grow, benefiting countless patients reliant on effective radiopharmaceuticals.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.