Location History:
- Pontodero, IT (2015)
- Pontedara, IT (2017)
- Pontedera, IT (2015 - 2021)
- Siena, IT (2016 - 2021)
Company Filing History:
Years Active: 2015-2021
Title: Inventor Maria Rosaria Romano: A Pioneer in Capsular Polysaccharide Research
Introduction
Maria Rosaria Romano, based in Pontedera, Italy, is a prominent inventor with a remarkable portfolio that includes 14 patents. Her innovative research primarily focuses on the purification and utilization of capsular polysaccharides, paving the way for advancements in biotechnology and pharmaceutical applications.
Latest Patents
Among her latest innovations is a groundbreaking method for releasing capsular polysaccharides from type 5 or type 8 cells. This invention encompasses a process that involves treating the cells with acid, which is followed by a series of purification steps. These may include enzymatic treatment to eliminate nucleic acid, protein, and peptidoglycan contaminants, as well as diafiltration to remove low molecular weight impurities. The method utilizes anion exchange chromatography to ensure the residual protein is effectively removed, resulting in a high yield of the capsular polysaccharide with minimal contamination from hyaluronic acid, protein, and nucleic acids. This invention also describes a composition involving type 5 or type 8 capsular polysaccharides that are obtainable through the outlined processes.
Career Highlights
Maria has contributed her expertise to well-known pharmaceutical companies, including GlaxoSmithKline Biologicals and Novartis AG. Her work in these organizations has been crucial in advancing scientific understanding and application of carbohydrate-based treatments.
Collaborations
In her professional journey, Maria has collaborated with notable colleagues such as Paolo Costantino and Francesco Berti. Their joint efforts have fostered significant progresses in the field of biotechnology and have played a pivotal role in the successful development of her patented technologies.
Conclusion
Maria Rosaria Romano exemplifies the spirit of innovation through her extensive contributions to capsular polysaccharide research. Her dedication and pioneering methods continue to influence the biopharmaceutical industry, underscoring the importance of her work in enhancing therapeutic solutions. Her patents not only highlight her ingenuity as an inventor but also promise to impact future developments in the field.