The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2015

Filed:

Dec. 30, 2010
Applicants:

Paolo Costantino, Colle Val d'Elsa, IT;

Francesco Berti, Colle Val D'Elsa, IT;

Francesca Micoli, Florence, IT;

Anna Kabanova, Bellinzona, CH;

Laura Serino, Monticiano, IT;

Maria Rosaria Romano, Pontodero, IT;

Marta Tontini, Lora Cluffenna, IT;

Inventors:

Paolo Costantino, Colle Val d'Elsa, IT;

Francesco Berti, Colle Val D'Elsa, IT;

Francesca Micoli, Florence, IT;

Anna Kabanova, Bellinzona, CH;

Laura Serino, Monticiano, IT;

Maria Rosaria Romano, Pontodero, IT;

Marta Tontini, Lora Cluffenna, IT;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); A61K 39/108 (2006.01); A61K 39/00 (2006.01); A61K 39/39 (2006.01);
U.S. Cl.
CPC ...
A61K 47/4833 (2013.01); A61K 39/0002 (2013.01); A61K 39/0258 (2013.01); A61K 39/39 (2013.01); A61K 2039/6068 (2013.01);
Abstract

proteins have been identified that are useful as carrier proteins to improve a response to a polysaccharide immunogen conjugated to such protein. In particular, AcfD precursor protein (orf3526 polypeptide), Flu antigen 43 protein (orf1364 polypeptide), and Sel1 repeat-containing protein (upec-5211 polypeptide) have been shown to be effective. Additionally, theseproteins can enhance the immune response to glucans, particularly fungal glucans.


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