Mamoru Shimizu

This inventor holds 12 USPTO granted patents, plus 1 CIPO patent and 2 EPO patents. Top assignees: Wave Life Sciences Ltd., Wave Life Sciences Japan, Inc., Chiralgen, Ltd.. Active years: 2013-2023.

USPTO Granted Patents = 12

% Patents Active = 100.0

CIPO Patents = 1 (Patent Applications = 1)

EPO Patents = 2 (Patent Applications = 1)

Average Co-Inventor Count = 2.4

ph-index = 10

Forward Citations = 409(Granted Patents)

Location History:

Chiba, JP (2013)
Kagoshima, JP (2016)
Okinawa, JP (2014 - 2019)
Uruma, JP (2017 - 2019)
Arlington, MA (US) (2020 - 2023)

Company Filing History:

7 out of 40

Wave Life Sciences Ltd.

patents

3 out of 7

Wave Life Sciences Japan, Inc.

The University of Tokyo

patents

where one patent can have more than one assignee

Years Active: 2013-2023

Loading Chart...

12 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 11718638 - Compounds, compositions and methods for synthesis (2023-08-08),

2. 11608355 - Technologies for oligonucleotide preparation (2023-03-21),

3. 11136346 - Asymmetric auxiliary group (2021-10-05),

4. 10696711 - Asymmetric auxiliary group (2020-06-30),

5. 10428019 - Chiral auxiliaries (2019-10-01),

6. 10329318 - Method for the synthesis of phosphorus atom modified nucleic acids (2019-06-25),

7. 10167309 - Asymmetric auxiliary group (2019-01-01),

8. 9695211 - Method for the synthesis of phosphorus atom modified nucleic acids (2017-07-04),

9. 9598458 - Asymmetric auxiliary group (2017-03-21),

10. 9394333 - Method for the synthesis of phosphorus atom modified nucleic acids (2016-07-19),

11. 8822671 - 2'-O-modified RNA (2014-09-02),

12. 8470987 - Protective group for synthesis of RNA and derivative (2013-06-25),

Title: The Innovations of Mamoru Shimizu

Introduction

Mamoru Shimizu, a notable inventor from Uruma, Japan, has made significant contributions to the field of synthesis and oligonucleotide preparation. With a total of 12 patents, his work has pushed the boundaries of what is possible in chemical synthesis, particularly in the areas of chiral auxiliaries and reagents.

Latest Patents

Shimizu's latest innovations include a comprehensive disclosure on compounds, compositions, and methods for synthesis. This particular patent outlines technologies that enhance stereoselective synthesis, providing essential reagents and methods for oligonucleotide synthesis. Moreover, his research focuses on the chirally controlled preparation of oligonucleotides, addressing the challenges in constructing complex internucleotidic linkages while ensuring high yields and stereoselectivity. The technologies highlighted also promise improved crude purity and yield in oligonucleotide preparation, which can significantly lower manufacturing costs.

Career Highlights

Throughout his career, Mamoru Shimizu has worked with esteemed companies, including Wave Life Sciences and Wave Life Sciences Japan, Inc. His dedication to advancing biochemical synthesis has established him as a prominent figure in the innovative landscape of chemistry.

Collaborations

Shimizu has collaborated with talented individuals in the field, including Takeshi Wada and Chandra Vargeese. These partnerships have fostered a creative environment that encourages the development of groundbreaking technologies in oligonucleotide preparation and synthesis.

Conclusion

Mamoru Shimizu's extensive portfolio of patents and his contributions to synthesis methodologies underscore his role as a pioneering inventor. His work not only addresses complex scientific challenges but also paves the way for advancements in the pharmaceutical and biotechnology industries.