Location History:
- Cambridge, GB (2012 - 2021)
- Cambridgeshire, GB (2023)
Company Filing History:
9 out of 338 
3 out of 832,891 Years Active: 2012-2025
Title: Ludovic Vallier – Innovator in Cholangiocyte Research
Introduction
Ludovic Vallier is a distinguished inventor based in Cambridge, GB, known for his significant contributions to the field of regenerative medicine. With a total of 11 patents to his name, Vallier has focused on expanding the understanding and application of cholangiocytes, as well as enhancing transcription control in cells.
Latest Patents
Among Vallier's latest patents are two groundbreaking innovations. The first, titled "Methods of expanding cholangiocytes," relates to the refinement of culture conditions that allow for the expansion of primary cholangiocytes in the form of cholangiocyte organoids (COs). This method involves the inhibition of canonical Wnt signaling while enhancing non-canonical Wnt/PCP signaling, which is vital for medical applications surrounding liver health.
The second patent, "Controllable transcription," introduces a stable method for incorporating an inducible cassette into various cell types. This innovative approach facilitates controlled transcription of genetic material, particularly in pluripotent stem cells (hPSCs), ensuring that the genetic information retains its functional integrity despite the insertion.
Career Highlights
Vallier's innovative work has been recognized within the realms of academia and industry. He has made substantial strides in cell biology, particularly in the context of stem cell research and regenerative medicine, paving the way for advancements in liver disease treatment and other medical applications.
Collaborations
Throughout his career, Vallier has collaborated with notable professionals in the field, including Roger Pedersen and Nicholas Hannan. These collaborations have contributed to the robust development of his patented techniques and have fostered an environment of innovation in cholangiocyte research.
Conclusion
Ludovic Vallier stands out as a pivotal figure in the innovation landscape of regenerative medicine. His patents not only enhance our scientific understanding but also have potent implications for future medical therapies. As he continues to pioneer new techniques and insights, Vallier's work promises to influence both research and clinical practices in significant ways.