Location History:
- San Diego, CA (US) (2009 - 2017)
- Omer, IL (2015 - 2022)
Company Filing History:
11 out of 1,187 
2 out of 343 
1 out of 8,373 
Years Active: 2009-2022
Title: Innovations and Contributions of Lital Alfonta in Biotechnology
Introduction
Lital Alfonta, based in San Diego, CA, is a prominent inventor in the field of biotechnology, holding an impressive portfolio of 13 patents. His work primarily focuses on advancing biochemical methodologies, specifically in the areas of protein engineering and biosensors.
Latest Patents
Among his latest innovations, Alfonta has developed a recombinant flavin-adenine dinucleotide glucose dehydrogenase and its various applications. This patent involves a recombinant protein that comprises an alpha subunit of FAD-GDH and a minimal cytochrome c peptide. It also includes an electrode coupled to this recombinant protein featuring a cofactor of a redox enzyme and methods for efficiently transferring electrons to an electrode. This innovation lays the groundwork for quantifying analytes such as glucose, showcasing its potential impact in medical diagnostics.
Another significant patent from Alfonta is related to the site-specific incorporation of redox active amino acids into proteins. This work details the development of orthogonal tRNAs and aminoacyl-tRNA synthetases that facilitate the incorporation of these unique amino acids. The methods introduced for identifying orthogonal pairs and producing proteins highlight the potential for enhanced functionality in engineered proteins.
Career Highlights
Lital Alfonta's career has been marked by significant contributions to leading research institutions. He has worked with The Scripps Research Institute and the Ben-Gurion University of the Negev Research and Development Authority. Through these institutions, he has been able to translate innovative ideas into practical applications, enhancing the scope of biotechnology research.
Collaborations
Throughout his professional journey, Alfonta has collaborated with esteemed colleagues, including Peter G. Schultz and Zhiwen Zhang. These partnerships reflect his commitment to collaborative research and the synergy that often arises from teamwork in scientific exploration.
Conclusion
Lital Alfonta continues to be a driving force in the field of biotechnology through his inventive contributions and collaborative efforts. His patents not only pave the way for advancements in biochemical applications but also exemplify the innovative spirit critical to progress in science and technology. As he continues to develop new methodologies, Alfonta's work has the potential to influence numerous industries, including healthcare and environmental science.