The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2014
Filed:
Jul. 11, 2012
Applicants:
Zhiwen Zhang, San Diego, CA (US);
Lital Alfonta, San Diego, CA (US);
Peter G. Schultz, La Jolla, CA (US);
Inventors:
Zhiwen Zhang, San Diego, CA (US);
Lital Alfonta, San Diego, CA (US);
Peter G. Schultz, La Jolla, CA (US);
Assignee:
The Scripps Research Institute, La Jolla, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C12N 9/00 (2006.01); C12N 15/74 (2006.01);
U.S. Cl.
CPC ...
Abstract
This invention provides methods and compositions for incorporation of an unnatural amino acid into a peptide using an orthogonal aminoacyl tRNA synthetase/tRNA pair. In particular, an orthogonal pair is provided to incorporate 5-hydroxy-L-tryptophan in a position encoded by an opal mutation.