The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 21, 2022

Filed:

Aug. 02, 2018
Applicant:

B. G. Negev Technologies and Applications Ltd., AT Ben-gurion University, Beer Sheva, IL;

Inventors:

Lital Alfonta, Omer, IL;

Raz Zarivach, Beer Sheva, IL;

Jennifer Grushka, Tel Aviv, IL;

Itay Algov, Kadima, IL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/09 (2006.01); C12N 9/04 (2006.01); G01N 27/327 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0006 (2013.01); C12Y 101/05 (2013.01); G01N 27/3271 (2013.01); C07K 2319/61 (2013.01);
Abstract

A recombinant protein, including: (a) alpha subunit of an FAD-GDH; and (b) a minimal cytochrome c peptide is provided. Additionally, an electrode coupled to a recombinant protein, the recombinant protein made of: (a) a cofactor of a redox enzyme; (b) a redox enzyme; (c) a linker moiety configured to link any one of: the cofactor or the enzyme to an electron transfer (ET) domain; and (d) an ET domain, is also provided. Methods for: (a) transferring an electron to an electrode, by coupling the recombinant protein an electrode; and (b) quantifying the amount of an analyte e.g., glucose are also provided.


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