Location History:
- Germantown, MD (US) (2013)
- Bridgewater, NJ (US) (2021)
- Cambridge, MA (US) (2022 - 2024)
Company Filing History:
7 out of 1,454 
1 out of 3,539 
1 out of 88 
Years Active: 2013-2025
Title: Innovator Lan Wu: Pioneering Trispecific Binding Proteins
Introduction: Lan Wu, an accomplished inventor based in Bridgewater, NJ, has made significant contributions to the field of biotechnology. With a total of eight patents to her name, she has focused on the development of innovative binding proteins that have potential applications in therapeutics, particularly in targeting complex diseases.
Latest Patents: Among her latest innovations are groundbreaking patents for trispecific binding proteins. These proteins consist of four polypeptide chains that create three distinct antigen binding sites, capable of specifically binding to one or more target proteins. Notably, her designs involve a first pair of polypeptides with dual variable domains in a cross-over orientation and a second pair featuring a single variable domain. Some of these innovative binding proteins are designed to target crucial proteins such as CD28 and CD3, as well as tumor-associated proteins. Additionally, some embodiments are aimed at binding HIV target proteins, showcasing the versatility and potential of her inventions in addressing various health challenges. The patents also detail methods for the synthesis of these proteins and their diverse uses in therapeutic applications.
Career Highlights: Lan Wu has built her career at notable organizations such as Sanofi and the United States Department of Health and Human Services. Through her work, she has contributed to advancing the understanding and application of trispecific binding proteins, establishing a notable presence in the biopharmaceutical sector.
Collaborations: Throughout her career, Lan Wu has collaborated with esteemed colleagues including Gary J. Nabel and Zhi-Yong Yang. These partnerships have fostered advancements in research and development, augmenting the impact of her innovative work.
Conclusion: Lan Wu exemplifies the spirit of innovation within the scientific community. With her extensive patent portfolio, particularly in trispecific binding proteins, she continues to pave the way for future advancements in medicine and biotechnology. Her contributions not only represent her expertise but also highlight the transformative potential of her innovations in improving healthcare outcomes.