Location History:
- Tokyo, JP (2004 - 2011)
- Toshima-ku, JP (2012)
- Hokkaido, JP (2014 - 2016)
- Sapporo, JP (2014 - 2023)
Company Filing History:
8 out of 9 
2 out of 314 
2 out of 879 
Years Active: 2004-2025
Title: Innovations by Inventor Kiyoshi Takayama
Introduction
Kiyoshi Takayama, an accomplished inventor based in Sapporo, Japan, has made significant contributions to the field of biotechnology. With a total of 9 patents to his name, his work primarily focuses on innovative methods for cell selection, nucleic acid production, and pharmaceutical compositions.
Latest Patents
Some of his latest patents include a "Method for selecting cells," "Method for producing nucleic acid," "Method for producing recombinant cells," "Method for producing target substance," and "Method for producing pharmaceutical composition." A key aspect of his innovation involves a reagent that provides a technique for selecting target cells that produce substances binding specifically to desired cell membrane proteins more rapidly and efficiently. This method utilizes a substrate with multiple microwells where a first cell, expressing a target cell membrane protein, is allowed to adhere. Candidate second cells coexist in these microwells, and the target substances they secrete are brought into contact with the first cell to identify the optimal match. One example of a target substance is an antibody, particularly one that binds to the human prostaglandin E2 receptor EP4 and inhibits its function.
Career Highlights
Kiyoshi has been associated with several reputable companies, including Nb Health Laboratory Co., Ltd. and Sekisui Chemical Co., Ltd. His career reflects a strong commitment to advancing biotechnological solutions that can significantly impact healthcare and pharmaceutical development.
Collaborations
Throughout his career, Kiyoshi has collaborated with notable colleagues such as Tomoko Shimizu and Yuji Urushibata. These collaborations have been instrumental in the development and success of his patents, enabling innovative solutions to emerge from their joint expertise.
Conclusion
In summary, Kiyoshi Takayama stands as a prominent figure in the realm of biotechnology, with numerous patents that underscore his innovative spirit. His methods for cell selection and pharmaceutical compositions hold promise for future advancements in medical science and therapeutics.