The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2016
Filed:
Sep. 18, 2014
Sekisui Chemical Co., Ltd., Osaka, JP;
Nb Health Laboratory Co., Ltd., Hokkaido, JP;
Naoki Nishiguchi, Ibaraki, JP;
Akiyoshi Hirayama, Ibaraki, JP;
Masahiro Furutani, Ibaraki, JP;
Tatsuo Shimizu, Osaka, JP;
Kiyoshi Takayama, Hokkaido, JP;
Tomoko Shimizu, Hokkaido, JP;
Kazuya Suzuki, Tokyo, JP;
SEKISUI CHEMICAL CO., LTD., Osaka, JP;
NB HEALTH LABORATORY CO., LTD., Hokkaido, JP;
Abstract
An anti-human-CC-motif-receptor-7 (anti-human-CCR7) antibody which is useful as a therapeutic agent for tissue fibrosis or cancer, and a pharmaceutical composition containing the anti-human CCR7 antibody, and the like is described. An anti-human CCR7 antibody specifically binding to an extracellular domain of human CCR7, having a heavy chain CDR3 containing an amino acid sequence represented by SEQ ID NO: 7, SEQ ID NO: 17, SEQ ID NO: 27, SEQ ID NO: 37, SEQ ID NO: 47, SEQ ID NO: 57, SEQ ID NO: 67, or SEQ ID NO: 77 is provided. Also provided is an anti-human CCR7 antibody having heavy chain CDRs 1-3 and light chain CDRs 1-3 containing amino acid sequences represented by SEQ ID NOs: 5-10, 15-20, 25-30, 35-40, 45-50, 55-60, 65-70, or 75-80. The anti-human CCR7 antibody of the present invention may be used as an active ingredient of a therapeutic agent for tissue fibrosis or cancer.