The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2012

Filed:

May. 01, 2007
Applicants:

Masato Kashimura, Toshima-ku, JP;

Madoka Kawamura, Toshima-ku, JP;

Toshifumi Asaka, Toshima-ku, JP;

Kiyoshi Takayama, Toshima-ku, JP;

Haruhisa Ogita, Toshima-ku, JP;

Inventors:

Masato Kashimura, Toshima-ku, JP;

Madoka Kawamura, Toshima-ku, JP;

Toshifumi Asaka, Toshima-ku, JP;

Kiyoshi Takayama, Toshima-ku, JP;

Haruhisa Ogita, Toshima-ku, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 17/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds represented by formula (I) and the formula (IV) have an inhibitory activity of MMP-9 production, therefore, are useful as a medicine agent with fewer side effects than conventional MMP enzyme activity inhibitors, as a prophylactic and therapeutic drug for oncogenic angiogenesis, chronic rheumatoid arthritis, vascular intimal thickening after a percutaneous coronary transluminal angioplasty, vascular atherosclerosis, hemorrhagic apoplexy, acute myocardial infarction, chronic heart failure, aneurysm, lung cancer metastasis, adult respiratory distress syndrome, asthma, interstitial pulmonary fibrosis, chronic rhinosinusitis, bronchitis or chronic obstructive pulmonary disease (COPD).


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