Osaka, Japan

Kazuhiko Ohne




Average Co-Inventor Count = 6.0

ph-index = 5

Forward Citations = 96(Granted Patents)


Location History:

  • Tsukuba, JP (2000 - 2001)
  • Osaka, JP (2004 - 2008)
  • Chuo-ku, JP (2015)
  • Tokyo, JP (2008 - 2016)

Company Filing History:


Years Active: 2000-2016

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10 patents (USPTO):Explore Patents

Title: Kazuhiko Ohne: Innovator in Cardiovascular Drug Development

Introduction

Kazuhiko Ohne is a prominent inventor based in Osaka, Japan. He has made significant contributions to the field of pharmaceuticals, particularly in the development of drugs for treating cardiovascular diseases. With a total of 10 patents to his name, his work has the potential to impact many lives.

Latest Patents

One of Kazuhiko Ohne's latest patents involves imidazopyridine compounds that serve as excellent drugs for treating or preventing cardiovascular diseases. These compounds enhance cGMP production through their action on soluble guanylate cyclase. Specifically, it was discovered that imidazopyridine compounds with a carbamoyl group at the 3-position and a substituent at the 8-position exhibit a potent cGMP production enhancing action. This innovation is particularly useful for addressing various soluble guanylate cyclase-related cardiovascular diseases.

Another significant patent focuses on a pharmaceutical composition aimed at treating or preventing cardiovascular diseases through sGC activities. The research revealed that imidazo[1,2-a]pyridine compounds with specific structural features activate sGC, making them valuable as active ingredients in pharmaceutical compositions. This work is especially relevant for conditions such as peripheral arterial diseases, intermittent claudication, critical limb ischemia, hypertension, and pulmonary hypertension.

Career Highlights

Kazuhiko Ohne has worked with notable companies in the pharmaceutical industry, including Astellas Pharma GmbH and Fujisawa Pharmaceutical Company, Ltd. His experience in these organizations has contributed to his expertise in drug development and innovation.

Collaborations

Throughout his career, Kazuhiko has collaborated with esteemed colleagues such as Kenichiro Imamura and Kozo Sawada. These partnerships have fostered a collaborative environment that enhances the research and development of new pharmaceutical solutions.

Conclusion

Kazuhiko Ohne's innovative work in the field of cardiovascular drug development showcases his commitment to improving healthcare through scientific advancements. His contributions are paving the way for new treatments that can significantly benefit patients suffering from cardiovascular diseases.

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