The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 22, 2005

Filed:

Feb. 20, 2001
Applicants:

Masahiro Neya, Osaka, JP;

Hitoshi Yamazaki, Osaka, JP;

Kazuhiko Ohne, Osaka, JP;

Yuki Sawada, Osaka, JP;

Tsuyoshi Mizutani, Osaka, JP;

Yoshimasa Imamura, Osaka, JP;

Noriko Mukai, Osaka, JP;

Inventors:

Masahiro Neya, Osaka, JP;

Hitoshi Yamazaki, Osaka, JP;

Kazuhiko Ohne, Osaka, JP;

Yuki Sawada, Osaka, JP;

Tsuyoshi Mizutani, Osaka, JP;

Yoshimasa Imamura, Osaka, JP;

Noriko Mukai, Osaka, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K031/55 ; C07D281/06 ; C07D417/04 ; C07D417/06 ; C07D417/12 ;
U.S. Cl.
CPC ...
Abstract

A compound of formula (I) in which Ris halo, lower alkoxy, optionally substituted aryl, optionally substituted aryloxy, optionally substituted heterecyclic group or optionally substituted lower alkynyl, Ris amidated carboxy, Ris hydrogen or acyl, Ar is aryl or heterocyclic group, X is thia, sulfinyl or sulfonyl, Y and Z are each lower alkylene, m and n are each an integer of 0 to 2, and a salt thereof, useful as inhibitors of matrix metalloproteinases (MMP) or the production of tumor necrosis factor α (TNF α)


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