Novato, CA, United States of America

Jonathan LeBowitz

USPTO Granted Patents = 23 

 

Average Co-Inventor Count = 2.6

ph-index = 8

Forward Citations = 358(Granted Patents)


Location History:

  • Frontenac, MO (US) (2008 - 2011)
  • Whitefish Bay, WI (US) (2010 - 2013)
  • Novato, CA (US) (2013 - 2022)

Company Filing History:


Years Active: 2008-2022

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23 patents (USPTO):Explore Patents

Title: Innovative Contributions of Jonathan LeBowitz in the Field of Lysosomal Targeting Technologies

Introduction: Jonathan LeBowitz, based in Novato, California, is a prominent inventor with an impressive portfolio consisting of 23 patents. His work focuses primarily on the development of advanced solutions for lysosomal targeting and therapeutic applications.

Latest Patents: Jonathan LeBowitz's latest patents showcase his innovative contributions to lysosomal targeting technologies. One such patent, titled "Lysosomal targeting peptides and uses thereof," provides enhanced compositions and methods for efficient lysosomal targeting, specifically utilizing GILT technology. This invention offers novel methods for targeting lysosomal enzymes using furin-resistant lysosomal targeting peptides and addresses binding affinity concerns related to the insulin receptor. Another significant patent, "Targeted therapeutic lysosomal enzyme fusion proteins and uses thereof," focuses on therapeutic fusion proteins designed to treat lysosomal storage diseases. This patent includes methods for treating Mucopolysaccharidosis Type IIIB (Sanfilippo B Syndrome) through the use of a targeted therapeutic fusion protein consisting of a lysosomal enzyme, a lysosomal targeting moiety like an IGF-II peptide, and a spacer peptide.

Career Highlights: Throughout his career, Jonathan has made remarkable strides in the biotechnology sector, contributing to significant advancements in therapeutic interventions for lysosomal disorders. He has worked with reputable companies, such as BioMarin Pharmaceutical Inc. and Zystor Therapeutics, Inc., where he played an integral role in research and development.

Collaborations: Jonathan has collaborated with distinguished professionals in the field, including Stephen M Beverley and Mika Aoyagi-Scharber. These collaborations have enabled the fusion of ideas, leading to groundbreaking innovations in lysosomal enzyme therapies.

Conclusion: Jonathan LeBowitz continues to be an influential figure in the realm of biotechnology, with his patents paving the way for new therapeutic advancements in treating lysosomal storage diseases. His dedication to innovation and collaboration highlights his significant contributions to the field and the improvement of patient outcomes worldwide.

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