Jonathan B Gilbert is an accomplished inventor based in Somerville, MA (US). He holds two patents that focus on advanced methods for intracellular delivery of biomolecules. His work has significant implications for immunology and biotechnology.

Latest Patents

One of his latest patents is titled "Intracellular delivery of biomolecules to induce tolerance." This invention provides methods for inducing tolerance and suppressing an immune response to an antigen by passing a cell suspension containing an anucleate cell through a constriction. The constriction deforms the cell, causing a perturbation that allows an antigen and/or tolerogenic factor to enter the cell. In some embodiments, the anucleate cell is delivered to an individual, and the antigen is processed in a tolerogenic environment to induce tolerance.

Another notable patent is "Intracellular delivery of biomolecules to cells comprising a cell wall." This disclosure pertains to methods for delivering a compound into a cell with a cell wall, including passing a cell suspension through a constriction. The deformation of the cell allows the compound to enter, enhancing the efficiency of delivery.

Career Highlights

Jonathan has worked with notable companies in the biotechnology sector, including Stemcell Technologies Canada Inc. and Sqz Biotechnologies Company. His experience in these organizations has contributed to his expertise in the field of biomolecular delivery systems.

Collaborations

He has collaborated with esteemed colleagues such as Howard Bernstein and Armon R Sharei, further enriching his research and development efforts.

Conclusion

Jonathan B Gilbert's innovative patents and career in biotechnology highlight his significant contributions to the field of immunology and biomolecular delivery. His work continues to pave the way for advancements in medical science.

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