The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2023
Filed:
Sep. 02, 2016
Applicant:
Sqz Biotechnologies Company, Watertown, MA (US);
Inventors:
Armon R. Sharei, Somerville, MA (US);
Howard Bernstein, Cambridge, MA (US);
Jonathan B. Gilbert, Somerville, MA (US);
Assignee:
SQZ Biotechnologies Company, Watertown, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/81 (2006.01); C12M 1/42 (2006.01); C12N 15/87 (2006.01); C12N 15/82 (2006.01); G01N 1/30 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
C12N 15/81 (2013.01); C12M 35/04 (2013.01); C12N 15/8206 (2013.01); C12N 15/8207 (2013.01); C12N 15/87 (2013.01); G01N 1/30 (2013.01); B82Y 5/00 (2013.01);
Abstract
The present disclosure pertains to methods for delivering a compound into a cell comprising a cell wall, including passing a cell suspension through a constriction, wherein said constriction deforms the cell comprising a cell wall, thereby causing a perturbation of the cell such that the compound enters the cell, wherein said cell suspension is contacted with the compound.