Company Filing History:
Years Active: 2022-2025
Title: Innovations of John Tomashek
Introduction
John Tomashek is a notable inventor based in Columbia, SC (US). He has made significant contributions to the field of enzymatic research, holding a total of 5 patents. His work focuses on enhancing the properties of various enzymes, which has important implications for drug analysis and treatment.
Latest Patents
Tomashek's latest patents include "Chimeric and other variant β-glucuronidase enzymes with enhanced properties." This invention provides enzymes that exhibit enhanced enzymatic activity, substrate range, pH range, temperature range, and enzyme stability compared to unmodified enzymes. Additionally, he has developed methods for using these variant enzymes for the hydrolysis of glucuronide substrates, including opiates and benzodiazepines. Another significant patent is for "Variant sulfatase enzymes with enhanced properties." This invention features mutated sulfatase enzymes that allow for accurate analysis of bodily samples for the presence of drugs. The methods provided include the hydrolysis of sulfate ester linkages in substrates such as opioids or steroids.
Career Highlights
John Tomashek is currently employed at Integrated Micro-chromatography Systems, Inc. His work at this company has allowed him to further his research and development in enzymatic applications. His innovative approaches have positioned him as a key figure in the field.
Collaborations
Some of his notable coworkers include Caleb Reece Schlachter and Lim Andrew Lee. Their collaborative efforts contribute to the advancement of enzymatic research and its applications.
Conclusion
John Tomashek's contributions to enzymatic research through his patents and work at Integrated Micro-chromatography Systems, Inc. highlight his role as an influential inventor in the field. His innovations continue to pave the way for advancements in drug analysis and treatment methodologies.