The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2022

Filed:

Jul. 31, 2019
Applicant:

Integrated Micro-chromatography Systems, Inc., Irmo, SC (US);

Inventors:

John Tomashek, Columbia, SC (US);

Caleb Reece Schlachter, Irmo, SC (US);

Pongkwan Sitasuwan, Columbia, SC (US);

Lim Andrew Lee, Columbia, SC (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/24 (2006.01); C12Q 1/37 (2006.01); C12Q 1/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2405 (2013.01); C12Q 1/005 (2013.01); C12Q 1/37 (2013.01); C12Y 301/06001 (2013.01); C12Y 302/01031 (2013.01);
Abstract

Blends of enzymes of the same enzyme class (same EC number), such as beta-glucuronidase enzyme blends, are provided that exhibit synergistic levels of activity across a range of substrates as compared to the activity levels of each enzyme in the blend individually. The blends also may exhibit a greater effective substrate range, as well as greater effective pH and/or temperature ranges as compared to single enzyme preparations. Predictive methods for determining optimal enzyme blends, methods for preparing enzyme blends, enzyme blend compositions, enzyme blend formulations and methods of using such enzyme blends are provided.


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