Location History:
- Duluth, MN (US) (2011 - 2016)
- Eveleth, MN (US) (2023)
Company Filing History:
Years Active: 2011-2023
Title: The Innovations of John R. Handley: Pioneering Advances in Polymer-Drug Conjugates
Introduction
John R. Handley, an innovative inventor based in Duluth, MN, has made significant contributions to the field of polymer-drug conjugates with his five patented inventions. His work at Nektar Therapeutics has led to advancements that enhance the stability and effectiveness of therapeutic compounds.
Latest Patents
Among his most recent patents is the innovation surrounding alkoxylation methods. This invention details a mixed-acid salt of a water-soluble polymer-drug conjugate. The significance of this mixed-salt lies in its stable formation and increased resistance to hydrolytic degradation compared to traditional forms. This advancement promises to improve the reliability and efficacy of polymer formulations in drug delivery.
Another notable patent focuses on the creation of a hydrohalide salt of a multi-arm polyethylene glycol-drug conjugate. Similar to his previous work, this invention demonstrates enhanced stability against hydrolytic degradation, providing a substantial improvement over the free base form of the conjugate. These innovations mark important strides in the design of drug delivery systems.
Career Highlights
John R. Handley's career at Nektar Therapeutics has been marked by these remarkable developments in polymer chemistry. His patents not only reflect his scientific acumen but also highlight his commitment to advancing therapeutic options for patients.
Collaborations
Throughout his career, Handley has collaborated closely with esteemed colleagues such as Antoni Kozlowski and Anthony G. Schaefer. These collaborations have fostered an environment of creativity and innovation, contributing to the successful outcomes of their projects and patents.
Conclusion
John R. Handley exemplifies the spirit of innovation and dedication in the field of polymer-drug conjugates. His latest patents pave the way for new possibilities in drug stability and efficacy, showcasing the importance of inventive minds in advancing medical science. As he continues to push the boundaries of research at Nektar Therapeutics, Handley remains a vital contributor to the world of pharmaceuticals.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.