The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 05, 2016
Filed:
Nov. 18, 2010
Anthony O. Chong, Huntsville, AL (US);
Seoju Lee, Madison, AL (US);
Bhalchandra V. Joshi, Madison, AL (US);
Brian Bray, Huntsville, AL (US);
Shaoyong Nie, Huntsville, AL (US);
Patrick L. Spence, Madison, AL (US);
Antoni Kozlowski, Huntsville, AL (US);
Samuel P. Mcmanus, Huntsville, AL (US);
Sachin Tipnis, Houston, TX (US);
David Swallow, Spring, TX (US);
John R. Handley, Duluth, MN (US);
Anthony G. Schaefer, Huntsville, AL (US);
Anthony O. Chong, Huntsville, AL (US);
Seoju Lee, Madison, AL (US);
Bhalchandra V. Joshi, Madison, AL (US);
Brian Bray, Huntsville, AL (US);
Shaoyong Nie, Huntsville, AL (US);
Patrick L. Spence, Madison, AL (US);
Antoni Kozlowski, Huntsville, AL (US);
Samuel P. McManus, Huntsville, AL (US);
Sachin Tipnis, Houston, TX (US);
Greg Lavaty, Sugar Land, TX (US);
David Swallow, Spring, TX (US);
John R. Handley, Duluth, MN (US);
Anthony G. Schaefer, Huntsville, AL (US);
Nektar Therapeutics, San Francisco, CA (US);
Abstract
Among other aspects, provided herein is a hydrohalide salt of a multi-arm water-soluble polyethylene glycol-drug conjugate, along with related methods of making and using the same. The hydrohalide salt is stably formed, and appears to be more resistant to hydrolytic degradation than the corresponding free base form of the conjugate.