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For the Inventor, By the Inventor

Ossining, NY, United States of America

John P Manfredi

USPTO Granted Patents = 20

Average Co-Inventor Count = 2.9

ph-index = 7

Forward Citations = 194(Granted Patents)


Location History:

  • North Brunswick, NJ (US) (1984)
  • New York, NY (US) (2000)
  • Ossining, NY (US) (1998 - 2009)
  • Salt Lake City, UT (US) (2003 - 2015)

Company Filing History:

goldMedal9 out of 16 
 
Cadus Technologies, Inc.
 patents
silverMedal5 out of 9 
 
Cadus Pharmaceutical Corp.
 patents
bronzeMedal4 out of 116 
 
Myriad Genetics, Inc.
 patents
4. 2 out of 832,680 
Other
 patents

Years Active: 1984-2015

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20 patents (USPTO):Explore Patents
1. 9216966 - Compounds for Alzheimer's disease (2015-12-22),
2. 7611854 - Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor (2009-11-03),
3. 7416881 - Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor (2008-08-26),
4. 7361498 - Yeast cells expressing modified G proteins and methods of use therefor (2008-04-22),
5. 7273747 - Cell having amplified signal transduction pathway responses and uses therefor (2007-09-25),
6. 7250263 - Methods and compositions for identifying receptor effectors (2007-07-31),
7. 7235648 - Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor (2007-06-26),
8. 7122305 - Methods and compositions for identifying receptor effectors (2006-10-17),
9. 7105309 - Yeast cells engineered to produce pheromone system protein surrogates and uses therefor (2006-09-12),
10. 6911311 - Method of detecting protein-protein interactions (2005-06-28),
11. 6864060 - Yeast cells expressing modified G proteins and methods of use therefor (2005-03-08),
12. 6828112 - Method of detecting protein-protein interactions (2004-12-07),
13. 6562576 - Yeast two-hybrid system and use thereof (2003-05-13),
14. 6551786 - Screen assay for selecting protein-protein interaction modulators (2003-04-22),
15. 6255059 - Methods for identifying G protein coupled receptor effectors (2001-07-03),

Title: Innovations and Contributions of John P. Manfredi

Introduction: John P. Manfredi is an accomplished inventor based in Ossining, NY, who holds an impressive portfolio of 20 patents. His work primarily focuses on advancements related to medical treatments and biotechnological innovations.

Latest Patents: Among his latest contributions are two significant patents. The first is centered on novel compounds for Alzheimer's disease, which involve indole and tetrahydroindole core compounds. These compounds are designed to address disorders associated with a defect in vesicular transport, particularly axonal transport. The second patent involves genetically engineered yeast cells capable of producing pheromone system protein surrogates. This invention allows for the expression of a surrogate of a pheromone system protein along with a peptide modulator, enhancing the effectiveness of a screening or selection system in yeast cells.

Career Highlights: John has an extensive career that includes his work at Cadus Technologies, Inc. and Cadus Pharmaceutical Corporation. His innovative efforts have contributed to the advancement of medical and biotechnological research, enhancing treatment possibilities for various disorders.

Collaborations: Throughout his career, John has collaborated with notable colleagues, including Christine A. Klein and Joshua Trueheart. These collaborations have played a crucial role in the advancement of his projects and research endeavors.

Conclusion: John P. Manfredi's body of work reflects his dedication to innovation in the fields of medicine and biotechnology. With numerous patents to his name, he continues to be a significant contributor to the understanding and treatment of complex diseases.

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