The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2006
Filed:
Oct. 01, 2002
Dana M. Fowlkes, Chapel Hill, NC (US);
James R. Broach, Princeton, NJ (US);
John P. Manfredi, Salt Lake City, UT (US);
Christine A. Klein, Salt Lake City, UT (US);
Andrew J. M. Murphy, Croton-On-Hudson, NY (US);
Jeremy I. Paul, Nyack, NY (US);
Joshua Trueheart, Concord, MA (US);
Dana M. Fowlkes, Chapel Hill, NC (US);
James R. Broach, Princeton, NJ (US);
John P. Manfredi, Salt Lake City, UT (US);
Christine A. Klein, Salt Lake City, UT (US);
Andrew J. M. Murphy, Croton-On-Hudson, NY (US);
Jeremy I. Paul, Nyack, NY (US);
Joshua Trueheart, Concord, MA (US);
Cadus Technologies, Inc., New York, NY (US);
Abstract
Yeast cells are engineered to express both a surrogate of a pheromone system protein (e.g., enzymes involved in maturation of α-factor, transporters of a-factor, pheromone receptors, etc.) and a potential peptide modulator of the surrogate, in such a manner that the inhibition or activation of the surrogate affects a screenable or selectable trait of the yeast cells. Various additional features improve the signal-to-noise ratio of the screening/selection system.