The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 03, 2001
Filed:
Jan. 17, 1996
Christine A. Klein, Ossining, NY (US);
Andrew J. M. Murphy, Montclair, NJ (US);
Dana M. Fowlkes, Chapel Hill, NC (US);
James Broach, Princeton, NJ (US);
John Manfredi, Ossining, NY (US);
Jeremy Paul, Nyack, NY (US);
Joshua Trueheart, South Nyack, NY (US);
Cadus Pharmaceutical Corporation, Tarrytown, NY (US);
Abstract
The present invention makes available a rapid, effective assay for screening and identifying pharmaceutically effective compounds that specifically interact with and modulate the activity of a cellular receptor or ion channel. The subject assay enables rapid screening of large numbers of polypeptides in a yeast expression library to identifying those polypeptides which induce or antagonize receptor bioactivity. The subject assay is particularly amenable for identifying surrogate ligands for orphan receptors.