John Leighton Mayo

Title: John Leighton Mayo: Innovator in Analyte Detection

Introduction

John Leighton Mayo is a notable inventor based in Penn Valley, California. He has made significant contributions to the field of analyte detection, holding a total of four patents. His innovative work focuses on developing devices and methods that enhance the detection of target analytes in fluid samples.

Latest Patents

Mayo's latest patents include a device and method for detecting a target analyte. This device features an inclined capillary tube designed to transport a sample fluid containing functionalized magnetic beads. These beads capture the target analyte from the sample fluid. The device also includes a well coupled with the inclined capillary tube, which contains a developer solution and receives the sample fluid. A movable magnet is attached to the inclined capillary tube, attracting the magnetic beads and moving them into the well. Additionally, a calorimeter is positioned adjacent to the well to detect heat output from an enzyme reaction associated with the captured target analyte, allowing for quantification of the analyte.

Another aspect of his patent involves a calorimeter specifically designed for detecting target analytes in fluid samples. This calorimeter includes a support structure and a hermetically-sealed, thermally decoupled central reaction zone. It features droplet transport regions that merge reagent droplets with sample droplets to form reaction droplets in the central reaction zone. The detection electronics are in communication with the central reaction zone, enabling the detection of heat produced by reactions between the target analyte and capture reagents.

Career Highlights

Throughout his career, John Leighton Mayo has worked with various companies, including Webb Diagnostics Technologies, Inc. His innovative contributions have significantly advanced the field of analyte detection.

Collaborations

Mayo has collaborated with notable individuals such as Franz Baudenbacher and Raymond Mernaugh. These collaborations have further enriched his work and contributions to the field.

Conclusion

John Leighton Mayo is a distinguished inventor whose work in analyte detection has led to significant advancements in the field. His innovative patents and collaborations highlight his commitment to enhancing detection methods, making a lasting impact on the industry.