The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 29, 2020

Filed:

Aug. 01, 2017
Applicants:

John Mayo, Nashville, TN (US);

Kevin Jones, Knoxville, TN (US);

Inventors:

John Mayo, Nashville, TN (US);

Kevin Jones, Knoxville, TN (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01K 17/00 (2006.01); G01N 33/53 (2006.01); C07K 14/47 (2006.01); C07K 16/08 (2006.01); C07K 16/18 (2006.01); C07K 16/44 (2006.01); G01N 33/02 (2006.01); G01N 33/18 (2006.01); G01N 33/68 (2006.01); B01L 3/00 (2006.01); A61K 39/00 (2006.01); G01N 1/02 (2006.01); G01N 33/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5304 (2013.01); C07K 14/47 (2013.01); C07K 16/08 (2013.01); C07K 16/18 (2013.01); C07K 16/44 (2013.01); G01N 33/02 (2013.01); G01N 33/18 (2013.01); G01N 33/6893 (2013.01); A61K 2039/505 (2013.01); B01L 3/5027 (2013.01); C12Q 2600/158 (2013.01); G01N 2001/022 (2013.01); G01N 2001/028 (2013.01); G01N 2033/0096 (2013.01);
Abstract

A device and method for detecting the presence of a target analyte in a fluid sample are provided. The device can include an inclined capillary tube for transporting a sample fluid containing a sample and functionalized magnetic beads. The functionalized magnetic beads capture the target analyte from the sample fluid. A well is coupled with the inclined capillary tube for containing a developer solution and for receiving the sample fluid. In at least one embodiment a magnet is movably attached to the inclined capillary tube for attracting the magnetic beads of the sample fluid and moving the magnetic beads into the well. A calorimeter is disposed adjacent to the well for receiving heat output from a reaction caused by an enzyme reaction associated with the captured target analyte in the developer solution thereby allowing detection and quantification of the target analyte.


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