The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 25, 2018

Filed:

Feb. 19, 2015
Applicants:

Franz Baudenbacher, Franklin, TN (US);

Raymond Mernaugh, Franklin, TN (US);

John Mayo, Nashville, TN (US);

Brad Lubbers, Madison, TN (US);

Robert G. Wiley, Franklin, TN (US);

Inventors:

Franz Baudenbacher, Franklin, TN (US);

Raymond Mernaugh, Franklin, TN (US);

John Mayo, Nashville, TN (US);

Brad Lubbers, Madison, TN (US);

Robert G. Wiley, Franklin, TN (US);

Assignee:

Other;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 25/20 (2006.01); G01N 33/543 (2006.01); B01L 3/00 (2006.01); G01N 25/48 (2006.01); G01K 17/00 (2006.01); B01L 7/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54306 (2013.01); B01L 3/502784 (2013.01); B01L 7/52 (2013.01); G01K 17/006 (2013.01); G01N 25/4806 (2013.01); G01N 33/54373 (2013.01); B01L 2200/147 (2013.01); B01L 2300/0636 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0819 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/0896 (2013.01); B01L 2300/1883 (2013.01);
Abstract

One aspect of the present disclosure relates to a calorimeter for detecting the presence of a target analyte in a fluid sample. The calorimeter can include a support structure, a hermetically-sealed, thermally decoupled central reaction zone associated with the support structure, at least one droplet transport region, and detection electronics. The at least one droplet transport region can be associated with the support structure and configured to merge a reagent droplet with a sample droplet including the fluid sample to form a reaction droplet in the central reaction zone. The detection electronics can be in electrical and/or thermal communication with the central reaction zone and associated with the support structure. The calorimeter can be configured to detect a heat of reaction produced by a reaction event between the target analyte and a capture reagent upon formation of the reaction droplet.


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