Schlieren, Switzerland

Johannes Sam

USPTO Granted Patents = 7 

 

Average Co-Inventor Count = 8.0

ph-index = 2

Forward Citations = 5(Granted Patents)


Company Filing History:


Years Active: 2020-2025

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7 patents (USPTO):

Title: **Innovative Contributions of Inventor Johannes Sam in Cancer Therapy**

Introduction

Johannes Sam is a notable inventor based in Schlieren, Switzerland, with a strong portfolio comprising seven patents. His innovative work primarily focuses on enhancing cancer therapies through advanced biotechnological approaches, aiming to improve treatment outcomes for patients.

Latest Patents

Among Johannes Sam's latest inventions are two significant patents that stand out for their potential impact in the medical field. The first is related to combination therapy utilizing targeted 4-1BB (CD137) agonists. This invention encompasses combination therapies using 4-1BB (CD137) agonists, particularly involving 4-1BBL trimer containing antigen-binding molecules, in conjunction with HER-2 targeting agents. This approach is aimed at improving cancer treatment methodologies.

The second patent concerns antibodies that bind to HLA-A2/WT1. This invention includes bispecific antigen-binding molecules intended for T cell activation. Additionally, it covers polynucleotides encoding such antibodies, as well as vectors and host cells that include these polynucleotides. The invention also outlines methods for producing the antibodies and their application in treating diseases.

Career Highlights

Johannes Sam holds a prestigious position at Hoffmann-La Roche, a leading company known for its commitment to advancing healthcare through innovative solutions. His career reflects a strong dedication to research and development, particularly in the realm of biopharmaceuticals aimed at oncology.

Collaborations

Throughout his career, Johannes has collaborated with esteemed colleagues such as Christian Klein and Ekkehard Moessner. These partnerships underscore his commitment to collaborative innovation and the exchange of ideas in the development of groundbreaking therapies.

Conclusion

Johannes Sam's contributions to the field of cancer therapy through his inventive patents signify an essential advancement in biomedicine. His work exemplifies the role of inventors in transforming healthcare and highlights the importance of collaboration in fostering innovation. As the landscape of cancer treatment evolves, inventions like those of Johannes Sam will likely play a crucial role in shaping future therapeutic approaches.

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