The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2023
Filed:
Mar. 16, 2020
Applicant:
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Inventors:
Marina Bacac, Schlieren, CH;
Claudia Ferrara Koller, Schlieren, CH;
Christian Klein, Schlieren, CH;
Mario Perro, Schlieren, CH;
Johannes Sam, Schlieren, CH;
Pablo Umaña, Schlieren, CH;
Wei Xu, Schlieren, CH;
Assignee:
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61P 35/00 (2006.01); C07K 14/705 (2006.01); C07K 16/46 (2006.01); A61K 39/00 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2887 (2013.01); A61K 39/001112 (2018.08); A61K 39/001117 (2018.08); A61K 39/001129 (2018.08); A61P 35/00 (2018.01); C07K 14/70532 (2013.01); C07K 14/70575 (2013.01); C07K 16/2809 (2013.01); C07K 16/2818 (2013.01); C07K 16/2827 (2013.01); C07K 16/2878 (2013.01); C07K 16/468 (2013.01); A61K 9/0019 (2013.01); A61K 2039/505 (2013.01); A61K 2039/545 (2013.01); C07K 2317/31 (2013.01); C07K 2317/52 (2013.01); C07K 2317/565 (2013.01); C07K 2317/71 (2013.01); C07K 2319/00 (2013.01);
Abstract
The present invention relates to combination therapies employing anti-CD20/anti-CD3 bispecific antibodies and 4-1BB (CD137) agonists, in particular 4-1BBL trimer containing antigen binding molecules, the use of these combination therapies for the treatment of cancer and methods of using the combination therapies.