The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 10, 2023

Filed:

Mar. 31, 2021
Applicant:

Hoffmann-la Roche Inc., Little Falls, NJ (US);

Inventors:

Maria Amann, Schlieren, CH;

Juergen Peter Bachl, Basel, CH;

Alexander Bujotzek, Penzberg, DE;

Carina Cantrill, Basel, CH;

Harald Duerr, Penzberg, DE;

Janine Faigle, Penzberg, DE;

Sabine Imhof-Jung, Penzberg, DE;

Christian Klein, Schlieren, CH;

Thomas Kraft, Penzberg, DE;

Estelle Marrer-Berger, Basel, CH;

Ekkehard Moessner, Schlieren, CH;

Laurene Pousse, Schlieren, CH;

Petra Rueger, Penzberg, DE;

Johannes Sam, Schlieren, CH;

Roland Staack, Penzberg, DE;

Dietrich Tuerck, Basel, CH;

Pablo Umana, Schlieren, CH;

Joerg Zielonka, Schlieren, CH;

Assignee:

Hoffmann-La Roche Inc., Little Falls, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/28 (2006.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01); C07K 16/30 (2006.01); C07K 16/46 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2809 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07K 16/2878 (2013.01); C07K 16/30 (2013.01); C07K 16/468 (2013.01); A61K 2039/505 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01);
Abstract

The invention relates to novel bispecific antigen binding molecules, comprising at least two antigen binding domains capable of specific binding to OX40 and a particular antigen binding domain capable of specific binding to Fibroblast Activation Protein (FAP), and to methods of producing these molecules and to methods of using the same.


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