Location History:
- Libertyvill, IL (US) (1999)
- Libertyville, IL (US) (1996 - 2007)
- Vernon Hills, IL (US) (2001 - 2007)
Company Filing History:
Years Active: 1996-2007
Title: The Innovative Mind of Jien-Heh J Tien
Introduction
Jien-Heh J Tien, based in Libertyville, IL, is a distinguished inventor with a remarkable portfolio of 19 patents. His innovative contributions in the field of antiviral compounds have significantly advanced research and therapeutic applications, particularly in combating HIV infections.
Latest Patents
Among his latest patents, Tien has developed retroviral protease inhibiting compounds, which serve as HIV protease inhibitors. The compounds discussed in his patent exhibit a specific formula that demonstrates potential effectiveness in inhibiting HIV infection. Additionally, he has made strides in the synthesis of acyclic nucleoside derivatives, introducing novel processes for producing antiviral valomaciclovir stearate. This process includes the reduction of an esterified guanine acetal to the corresponding alcohol, which is then reacted with an activated amino acid. These methodologies are notable for their amenability to one-pot reactions, simplifying the synthesis process.
Career Highlights
Tien has made substantial contributions while working at prominent companies such as Abbott Laboratories Corporation and Mediver Ab. His innovative work in these companies has played a critical role in the advancement of antiviral therapies, reinforcing his reputation as a leading inventor in the pharmaceutical field.
Collaborations
Throughout his career, Jien-Heh J Tien has collaborated with esteemed colleagues, including Michael S Allen and Howard E Morton. These collaborations have facilitated the exchange of ideas and fostered an environment of innovation that has led to groundbreaking discoveries in antiviral compounds.
Conclusion
Jien-Heh J Tien's substantial contributions through his patents and collaborations highlight his dedication to advancing medical research and treatment options. His work encapsulates the spirit of innovation and exemplifies the critical role inventors play in developing solutions that address global health challenges.