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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 5892008 B1

PDFFull Text
Date of Patent:
Apr. 06, 1999

Filed:

Dec. 16, 1997

Process for the preparation of 6-o-methyl erythromycin a using 9-hydroxy

Applicant:
Inventors:

Yi-Yin Ku, Buffalo, IL (US);

David A Riley, Kenosha, WI (US);

Elaine C Lee, Wheeling, IL (US);

Jien-Heh Tien, Libertyvill, IL (US);

Assignee:

Abbott Laboratories, Abbott Park, IL (US);

Attorneys:

Chen; Portia

Anand; Mona

Primary Examiner:

Gary L Kunz

Int. Cl.
CPC ...
C07H / ; C07H / ;
U.S. Cl.
CPC ...
536 185 ; 536-72 ;
Abstract

The claimed invention provides a novel method of preparing 6-O-methyl erythromycin A. The process comprises the steps of reducing the 9-keto group of erythromycin A to form a 9-hydroxy erythromycin A, protecting the 9-, 2'-, and/or 4'-hydroxyl groups of erythromycin A, selectively methylating the 6-position of the 9-hydroxy erythromycin A derivative, deprotecting the hydroxyl groups and oxidizing the 9-hydroxyl to afford 6-O-methyl erythromycin A.

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Ku, Yi-Yin. (1999). Process for the preparation of 6-o-methyl erythromycin a using 9-hydroxy (U.S. Patent No. 5892008). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5892008

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