Location History:
- Charleston, SC (US) (2006)
- Chapel Hill, NC (US) (2005 - 2024)
Company Filing History:
10 out of 1,270 
2 out of 612 
2 out of 1,991 
Years Active: 2005-2025
Title: Innovations and Contributions of Inventor Jian Liu
Introduction
Jian Liu is a prominent inventor based in Chapel Hill, NC (US), known for his significant contributions to the field of biochemistry and medicinal chemistry. With a total of 12 patents to his name, Liu has made remarkable advancements in the development of therapeutic compounds.
Latest Patents
Among his latest patents, Liu has developed sulfated oligosaccharides that exhibit anti-inflammatory activity. These small molecule compounds, including non-anticoagulant heparan sulfate oligosaccharide molecules, have the capability to interact with high mobility group box 1 (HMGB1) proteins. This interaction is sufficient to influence the relationship between the HMGB1 protein and the receptor for advanced glycation end products (RAGE). Additionally, Liu has provided methods for treating Paracetamol (APAP) overdose in subjects. Another notable patent involves the enzymatic synthesis of homogeneous chondroitin sulfate oligosaccharides. This patent outlines methods for synthesizing structurally defined homogeneous chondroitin sulfate oligosaccharides at high yields, ranging from 3-mers to 15-mers.
Career Highlights
Liu has held positions at esteemed institutions such as the University of North Carolina at Chapel Hill and Rensselaer Polytechnic Institute. His work at these institutions has been pivotal in advancing research in his field.
Collaborations
Throughout his career, Liu has collaborated with notable colleagues, including Yongmei Xu and Rafal Pawlinski. These collaborations have further enriched his research and contributions to the scientific community.
Conclusion
Jian Liu's innovative work and numerous patents reflect his dedication to advancing medical science and therapeutic solutions. His contributions continue to have a significant impact on the field of biochemistry.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.