The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2024
Filed:
Mar. 12, 2018
Applicant:
The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);
Inventors:
Jian Liu, Chapel Hill, NC (US);
Zhangjie Wang, Changchun, CN;
Po-Hung Hsieh, Pasadena, CA (US);
Yongmei Xu, Durham, NC (US);
Assignee:
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/727 (2006.01); A61K 38/48 (2006.01); C08B 37/00 (2006.01); C12P 19/04 (2006.01); C12P 19/18 (2006.01); A61P 7/02 (2006.01);
U.S. Cl.
CPC ...
A61K 31/727 (2013.01); A61K 38/4846 (2013.01); A61P 7/02 (2018.01); C08B 37/0075 (2013.01); C12P 19/04 (2013.01); C12P 19/18 (2013.01);
Abstract
Heparin compounds and synthetic heparin analogues having short acting anticoagulant activity are provided. Methods of synthesizing such heparin compounds, including chemoenzymatic pathways using sulfotransferase enzymes are provided. Methods of treating subjects in need of anticoagulant activity are provided.